17 PATIENT COUNSELING INFORMATION
Inform patients that Tigan can cause serious adverse reactions. Instruct patients to discontinue Tigan and contact a healthcare provider immediately if the following serious reactions occur:
- Acute Dystonic Reactions and Other Extrapyramidal Symptoms [see Warnings and Precautions (5.1)]
- Other CNS Reactions [see Warnings and Precautions (5.2, 5.3)]
- Hepatotoxicity [see Warnings and Precautions (5.4)]
Effects on the Ability to Drive or Operate Machinery
Advise patients that Tigan can cause drowsiness and may impair their judgment, thinking, or motor skills required for tasks such as driving a motor vehicle or operating machinery. Inform patients not to operate motor vehicles or other dangerous machinery until they are reasonably certain that Tigan does not affect them adversely [see Warnings and Precautions (5.5)].
Inform patients that use of alcohol or concomitant treatment with other CNS-acting drugs can precipitate or worsen CNS depression and/or EPS [see Drug Interactions (7.1, 7.2)]. Instruct patients to avoid alcohol and to tell their health care providers when they start taking any concomitant medication.